Marko Marin makes his first Chelsea start, replacing Eden Hazard on the left flank, while Frank Lampard captains the side from deep midfield.
Lampard is partnered in the middle by Oscar, while Cesar Azpilicueta is recalled at right-back with Gary Cahill suspended. Branislav Ivanovic moves inside, and Ryan Bertrand starts in place of the rested Ashley Cole at left-back.
Among the subs are youngsters George Saville, Nathan Ake and Lucas Piazon.
Chelsea are expected to line up in the following 4-2-3-1 formation:
1 Petr Cech
28 Cesar Azpilicueta
2 Branislav Ivanovic
4 David Luiz
34 Ryan Bertrand
8 Frank Lampard (c)
13 Victor Moses
10 Juan Mata
21 Marko Marin
9 Fernando Torres
Subs: 22 Ross Turnbull, 19 Paulo Ferreira, 3 Ashley Cole, 57 Nathan Ake, 56 George Saville, 35 Lucas Piazon, 17 Eden Hazard.
Leeds United are as follows:
Ashdown, Peltier (c), Leeds, Pearce, Green, Thomas, Becchio, Brown, Tonge, Diouf, Byram.
Subs: Kenny, Varney, White, Norris, Gray, Somma, McCormack.
The referee is Andre Marriner.