John Terry returns to the defence where he will partner David Luiz. Fernando Torres leads the attack with Demba Ba cup-tied.
John Mikel Obi retains his place having come on as a sub at Old Trafford with Frank Lampard on the bench. Eden Hazard also starts.
Steaua Bucharest are unchanged from the first leg.
Chelsea are expected to line up in the following 4-2-3-1 formation:
1 Petr Cech
28 Cesar Azpilicueta
4 David Luiz
26 John Terry (c)
3 Ashley Cole
12 John Mikel Obi
17 Eden Hazard
10 Juan Mata
9 Fernando Torres
Substitutes: 22 Ross Turnbull, 19 Paulo Ferreira, 24 Gary Cahill, 34 Ryan Bertrand, 30 Yossi Benayoun, 8 Frank Lampard, 13 Victor Moses.
Steaua Bucharest are expected to line up in the following 4-2-3-1 formation:
Tatarusanu; Rapa, Szukala, Chiriches, Latovlevici; Bourceanu (c), Pintilii; Popa, Chipciu, Tanase; Rusescu.
Substitutes: Stanka (GK), Gardos, Filip, Prepelita, Iancu, Leandro Tatu, Adi Sobrinho.
The referee is Stéphane Lannoy from France.
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