Chelsea travel to Old Trafford looking to keep their top-four hopes alive, with the Blues sitting in fourth, three points behind their opponents.
With Jose Mourinho and Antonio Conte at war in recent weeks, it promises to be a tight affair, with neither side willing to give too much away.
Here’s who would make it into a combined XI from the two teams:
1. GK: David de Gea (Man Utd)
Probably the easiest choice, David de Gea is a must, with his performances being the lynchpin to Man Utd’s return to prominence over the past two seasons, not least in the midweek 0-0 draw at Sevilla, where he made eight saves to keep the Spaniards out.
Whilst Thibaut Courtois is a fine keeper amongst the best in Europe, de Gea is a cut above, with the Spaniard arguably surpassing Manuel Neuer as the world’s best shot-stopper.
2. RB: Cesar Azpilicueta (Chelsea)
Being the most consistent defender in the Premier League, Azpilicueta is an obvious choice, with the Spaniard a rock which the defence can be built around.
Bought for just £7million in 2012, he has been a steady hand in the backline, equally comfortable at either full-back position or in his current role at centre-back.
3. CB: Eric Bailly (Man Utd)
After several unconvincing defensive additions in recent years, the arrival of Eric Bailly from Villarreal last season garnered comparisons with Rio Ferdinand after the £30million buy made a cultured start.
The Ivorian is a cut above the likes of Marcos Rojo and Phil Jones and Jose Mourinho will be delighted to have him back fit for the rest of the season.
4. CB: Andreas Christensen (Chelsea)
Despite making a crucial error that led to Barcelona’s away goal on Tuesday, Christensen is the main man in the Chelsea back three and will remain in the line-up.
The Dane has had a breakthrough season, drawing praise from John Terry and others as he seems to be the first youth team prospect to come up since the Englishman almost two decades ago.
5. LB: Marcos Alonso (Chelsea)
With his competitor, Ashley Young, being a winger by trade, this was an easy decision, although the Englishman has coped admirably in his new role at left-back.
Alonso has built on his excellent first season by adding more goals to his game, netting seven times already to be the highest-scoring defender in Europe. Only Eden Hazard and Alvaro Morata have scored more for the Blues in the Premier League, with the Spaniard a huge threat on the left flank.
6. CDM: N’Golo Kante (Chelsea)
After winning the PFA Player of the Year in Chelsea’s run to the title last year, Kante has had a downturn in form by his lofty standards, though it has by no means been a bad season for the Frenchman.
On his day, he remains relentless chasing down attackers and still ranks amongst the very best defensive midfielders in the world.
7. CDM: Nemanja Matic (Man Utd)
It was widely seen as a mistake for Chelsea to let Nemanja Matic go to their rivals last summer, and it has only been proven this season, with the Serbian excelling after being reunited with Jose Mourinho.
The Blues’ misery has been compounded by the fact that his replacement, Tiemoue Bakayoko, has had a poor first season at Stamford Bridge, recently being sent off after half an hour in a 4-1 win over Watford.
8. RW: Willian (Chelsea)
Willian has long been one of Chelsea’s most reliable players, with the Brazilian the only person to come out of their torrid 2015-16 season under Jose Mourinho with any credit.
Having hit the post twice and scored the opener against Barcelona, he is in good form and will be looking to strike at Old Trafford.
9. CAM: Eden Hazard (Chelsea)
An unquestionable selection, Hazard remains one of the Premier League’s very best players and is having a great season, hitting something approaching his best in the past few weeks.
With the ability to dictate the game and score a goal out of nothing, United will need to keep him quiet if they want to get something from Sunday’s game.
10. LW: Alexis Sanchez (Man Utd)
Whilst not setting the world alight since his move from Arsenal last month, Alexis Sanchez has made a solid start to his United career, scoring his first goal in the recent 2-0 win over Huddersfield.
The Chilean adds a formidable option to Jose Mourinho’s attack, able to interchange seamlessly with the likes of Rashford and Lingard to devastating effect.
11. ST: Marcus Rashford (Man Utd)
A left-field choice, perhaps. with both sides having splashed out a combined £135million to buy new number nines in Alvaro Morata and Romelu Lukaku last summer.
However, with Morata struggling for goals and the Belgian goal-shy on big occasions, Rashford represents the best option. Despite being used on the wing for most of the season, the 20-year-old excels through the middle in his natural position up front.
The Englishman offers blistering pace and a direct style that can unlock a tight game, as was shown when he opened the scoring for United in last season’s 2-0 win over the champions.